TRPV2

GENERAL INFORMATION

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Gene name

TRPV2

Gene description

Transient receptor potential cation channel, subfamily V, member 2

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal tissues displayed moderate to strong cytoplasmic staining. Adipocytes, liver, placenta and stomach were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA044993
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TRPV2 (HGNC Symbol)

Synonyms

VRL, VRL-1, VRL1

Description

Transient receptor potential cation channel, subfamily V, member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p11.2

Chromosome location (bp)

16415542 - 16437003

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000187688 (version 78.38)

Entrez gene

51393

UniProt

Q9Y5S1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5S1

Antibodypedia

TRPV2 antibodies


PROTEIN BROWSER

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ENST00000338560
 
ENST00000455666
 
ENST00000577277
 
ENST00000577865
 
ENST00000580788
 
ENST00000581560
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPV2-001 ENSP00000342222
ENST00000338560
Q9Y5S1
Show all »
Show » Show » 764 86 No 6
TRPV2-006 ENSP00000390014
ENST00000455666
Show » Show » 266 29 No 0
TRPV2-007 ENSP00000464850
ENST00000577277
Show » 77 8.4 No 1
TRPV2-009 ENSP00000465609
ENST00000581560
K7EKG5
Show all »
Show » Show » 138 15.6 No 1
TRPV2-010 ENSP00000466130
ENST00000580788
Show » 96 10.4 No 1
TRPV2-011 ENSP00000467593
ENST00000577865
K7EPY7
Show all »
Show » Show » 90 9.9 No 0