ADH1A

GENE INFORMATION

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Gene name

ADH1A (HGNC Symbol)

Synonyms

ADH1

Description

alcohol dehydrogenase 1A (class I), alpha polypeptide (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010]

Chromosome

4 (Chromosome progress)

Cytoband

q23

Chromosome location (bp)

100197524 - 100212185

Ensembl

ENSG00000187758 (version 73.37)

Entrez gene

124

UniProt

P07327 (UniProt - Evidence at protein level)

neXtProt

NX_P07327

Antibodypedia

ADH1A antibodies
 

PROTEIN VIEW

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ADH1A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADH1A-001 ENSP00000209668
ENST00000209668
P07327
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