H2AFX

GENE INFORMATION

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Gene name

H2AFX (HGNC Symbol)

Synonyms

H2AX

Description

H2A histone family, member X (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

118964564 - 118966177

Ensembl

ENSG00000188486 (version 73.37)

Entrez gene

3014

UniProt

P16104 (UniProt - Evidence at protein level)

neXtProt

NX_P16104

Antibodypedia

H2AFX antibodies
 

PROTEIN VIEW

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H2AFX-001
 
H2AFX-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

H2AFX-001 ENSP00000434024
ENST00000530167
P16104
Show all »
Show » Show » 143 15.1 No 0
H2AFX-002 ENSP00000364310
ENST00000375167
P16104
Show all »
Show » Show » 143 15.1 No 0