SRSF10

GENE INFORMATION

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Gene name

SRSF10 (HGNC Symbol)

Synonyms

FUSIP1, FUSIP2, NSSR, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2

Description

serine/arginine-rich splicing factor 10 (HGNC Symbol)

Entrez gene summary

This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.[provided by RefSeq, Jul 2010]

Chromosome

1 (Chromosome progress)

Cytoband

p36.11

Chromosome location (bp)

24291294 - 24307417

Ensembl

ENSG00000188529 (version 73.37)

Entrez gene

10772

UniProt

O75494 (UniProt - Evidence at protein level)

neXtProt

NX_O75494

Antibodypedia

SRSF10 antibodies
 

PROTEIN VIEW

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SRSF10-001
 
SRSF10-002
 
SRSF10-003
 
SRSF10-005
 
SRSF10-006
 
SRSF10-012
 
SRSF10-014
 
SRSF10-015
 
SRSF10-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRSF10-001 ENSP00000420195
ENST00000492112
O75494
Show all »
Show » 262 31.3 No 0
SRSF10-002 ENSP00000342913
ENST00000344989
O75494
Show all »
Show » 183 22.2 No 0
SRSF10-003 ENSP00000344149
ENST00000343255
O75494
Show all »
Show » 261 31.2 No 0
SRSF10-005 ENSP00000388991
ENST00000453840
O75494
Show all »
Show » 182 22.1 No 0
SRSF10-006 ENSP00000363576
ENST00000374452
O75494
Show all »
Show » 173 21 No 0
SRSF10-012 ENSP00000473291
ENST00000495785
Q6IQ42
Show all »
Show » 69 8.3 No 0
SRSF10-014 ENSP00000363577
ENST00000374453
Q5JRI1
Show all »
Show » 172 20.9 No 0
SRSF10-015 ENSP00000473293
ENST00000473858
R4GMP8
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40 4.6 No 0
SRSF10-017 ENSP00000419813
ENST00000484146
O75494
Show all »
Show » 165 20.1 No 0