RHCE

GENE INFORMATION

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Gene name

RHCE (HGNC Symbol)

Synonyms

CD240CE, RH

Description

Rh blood group, CcEe antigens (HGNC Symbol)

Entrez gene summary

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p36.11

Chromosome location (bp)

25688740 - 25756683

Ensembl

ENSG00000188672 (version 73.37)

Entrez gene

6006

UniProt

P18577 (UniProt - Evidence at protein level)

neXtProt

NX_P18577

Antibodypedia

RHCE antibodies
 

PROTEIN VIEW

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 « 
 
RHCE-001
 
RHCE-002
 
RHCE-004
 
RHCE-005
 
RHCE-023
 
RHCE-024
 
RHCE-025
 
RHCE-201
 
RHCE-202
 
RHCE-203
 
RHCE-204
 
RHCE-205
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RHCE-001 ENSP00000294413
ENST00000294413
P18577
Show all »
Show » Show » 417 45.5 No >9
RHCE-002 ENSP00000334570
ENST00000349438
Q5VSJ8
Show all »
Show » Show » 354 38.6 No 9
RHCE-004 ENSP00000345084
ENST00000340849
Q5VSJ7
Show all »
Show » Show » 267 28.6 No 7
RHCE-005 ENSP00000311185
ENST00000349320
Q5VSJ9
Show all »
Show » Show » 401 43.9 No >9
RHCE-023 ENSP00000344485
ENST00000346452
E7EQ47
Show all »
Show » Show » 266 29.2 No 7
RHCE-024 ENSP00000435401
ENST00000533771
E9PKB3
Show all »
Show » 55 6.3 No 1
RHCE-025 ENSP00000431741
ENST00000527747
J7GUD8
Show all »
Show » 77 8.3 No 0
RHCE-201 ENSP00000243186
ENST00000243186
E7EMF2
Show all »
Show » Show » 372 40.4 No >9
RHCE-202 ENSP00000363472
ENST00000374352
Q5VSJ9
Show all »
Show » Show » 401 43.9 No >9
RHCE-203 ENSP00000415417
ENST00000413854
E7EU00
Show all »
Show » Show » 396 43.6 No >9
RHCE-204 ENSP00000392809
ENST00000425135
E7EN29
Show all »
Show » Show » 308 34.1 No 8
RHCE-205 ENSP00000416275
ENST00000455194
E7EWZ5
Show all »
Show » Show » 312 33.7 No 9