LIPI

GENERAL INFORMATION

? »

Gene name

LIPI

Gene description

Lipase, member I

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enriched (thyroid gland)
GTEx:Tissue enhanced (thyroid gland)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA029950
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enriched (thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (thyroid gland)

Organ

Expression



GENE INFORMATION

? »

Gene name

LIPI (HGNC Symbol)

Synonyms

CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5

Description

Lipase, member I (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Chromosome

21

Cytoband

q11.2

Chromosome location (bp)

14108813 - 14210891

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188992 (version 78.38)

Entrez gene

149998

UniProt

Q6XZB0 (UniProt - Evidence at protein level)

neXtProt

NX_Q6XZB0

Antibodypedia

LIPI antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000344577
 
ENST00000400211
 
ENST00000536861
 
ENST00000614229
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LIPI-001 ENSP00000343331
ENST00000344577
Q6XZB0
Show all »
Show » Show » 481 55.2 No 0
LIPI-002 ENSP00000383072
ENST00000400211
Q5D1Q2
Show all »
Show » 141 15.7 No 0
LIPI-201 ENSP00000440381
ENST00000536861
Q6XZB0
Show all »
Show » Show » 451 51.8 No 0
LIPI-202 ENSP00000482652
ENST00000614229
Q5D1Q2
Show all »
Show » Show » 421 48.6 No 0