ALKBH2

GENE INFORMATION

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Gene name

ALKBH2 (HGNC Symbol)

Synonyms

ABH2, MGC90512

Description

alkB, alkylation repair homolog 2 (E. coli) (HGNC Symbol)

Entrez gene summary

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]

Chromosome

12 (Chromosome progress)

Cytoband

q24.11

Chromosome location (bp)

109525996 - 109531436

Ensembl

ENSG00000189046 (version 73.37)

Entrez gene

121642

UniProt

Q6NS38 (UniProt - Evidence at protein level)

neXtProt

NX_Q6NS38

Antibodypedia

ALKBH2 antibodies
 

PROTEIN VIEW

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ALKBH2-001
 
ALKBH2-003
 
ALKBH2-005
 
ALKBH2-007
 
ALKBH2-008
 
ALKBH2-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALKBH2-001 ENSP00000343021
ENST00000343075
Q6NS38
Show all »
Show » Show » 261 29.3 No 0
ALKBH2-003 ENSP00000399820
ENST00000440112
Q6NS38
Show all »
Show » Show » 157 17.1 No 0
ALKBH2-005 ENSP00000443042
ENST00000536242
F5H5X2
Show all »
Show » 150 16.6 No 0
ALKBH2-007 ENSP00000398181
ENST00000429722
Q6NS38
Show all »
Show » Show » 261 29.3 No 0
ALKBH2-008 ENSP00000444103
ENST00000536358
F5GZZ0
Show all »
Show » 121 13.4 No 0
ALKBH2-009 ENSP00000474702
ENST00000543444
149 16.6 No 0