SH2D5

GENERAL INFORMATION

? »

Gene name

SH2D5

Gene description

SH2 domain containing 5

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (cerebral cortex, placenta, testis)
GTEx:Group enriched (cerebral cortex, hippocampus, testis)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic and nuclear expression in CNS.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining not consistent with RNA expression data. Presumed off target binding observed and disregarded. Pending retesting.

Data reliability

Uncertain based on 1 antibody.
HPA030182
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Hippocampus

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, placenta, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebral cortex, hippocampus, testis)

Organ

Expression



GENE INFORMATION

? »

Gene name

SH2D5

Synonyms

Description

SH2 domain containing 5 (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

p36.12

Chromosome location (bp)

20719732 - 20732837

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000189410 (version 78.38)

Entrez gene

400745

UniProt

Q6ZV89 (UniProt - Evidence at protein level)

neXtProt

NX_Q6ZV89

Antibodypedia

SH2D5 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000375031
 
ENST00000444387
 
ENST00000447746
 
ENST00000517430
 
ENST00000518294
 
ENST00000519434
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SH2D5-001 ENSP00000364171
ENST00000375031
Q6ZV89
Show all »
Show » 339 37.4 No 0
SH2D5-003 ENSP00000406026
ENST00000444387
Q6ZV89
Show all »
Show » Show » 423 46.8 No 0
SH2D5-004 ENSP00000428153
ENST00000518294
E5RJW5
Show all »
Show » Show » 131 14.7 No 0
SH2D5-005 ENSP00000408509
ENST00000447746
J3KQT6
Show all »
Show » 134 14.8 No 0
SH2D5-006 ENSP00000428656
ENST00000517430
E5RGV2
Show all »
Show » Show » 126 14.2 No 0
SH2D5-007 ENSP00000430115
ENST00000519434
E5RGJ3
Show all »
Show » 70 7.9 No 0