SERPINA3

GENE INFORMATION

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Gene name

SERPINA3 (HGNC Symbol)

Synonyms

AACT, ACT, alpha-1-antichymotrypsin

Description

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q32.13

Chromosome location (bp)

95078714 - 95090392

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196136 (version 75.37)

Entrez gene

12

UniProt

P01011 (UniProt - Evidence at protein level)

neXtProt

NX_P01011

Antibodypedia

SERPINA3 antibodies
 

PROTEIN VIEW

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SERPINA3-002
 
SERPINA3-003
 
SERPINA3-006
 
SERPINA3-007
 
SERPINA3-009
 
SERPINA3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINA3-002 ENSP00000450540
ENST00000467132
P01011
Show all »
Show » Show » 423 47.7 Yes 0
SERPINA3-003 ENSP00000451119
ENST00000482740
G3V3A0
Show all »
Show » Show » 205 23.4 No 0
SERPINA3-006 ENSP00000452246
ENST00000555820
G3V595
Show all »
Show » 46 4.8 No 0
SERPINA3-007 ENSP00000376795
ENST00000393080
P01011
Show all »
Show » Show » 423 47.7 Yes 0
SERPINA3-009 ENSP00000452476
ENST00000556968
P01011
Show all »
Show » Show » 216 24 Yes 0
SERPINA3-201 ENSP00000376793
ENST00000393078
P01011
Show all »
Show » Show » 423 47.7 Yes 0