ACADSB

GENE INFORMATION

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Gene name

ACADSB (HGNC Symbol)

Synonyms

ACAD7, SBCAD

Description

acyl-CoA dehydrogenase, short/branched chain (HGNC Symbol)

Entrez gene summary

Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q26.13

Chromosome location (bp)

124768495 - 124817827

Ensembl

ENSG00000196177 (version 73.37)

Entrez gene

36

UniProt

P45954 (UniProt - Evidence at protein level)

neXtProt

NX_P45954

Antibodypedia

ACADSB antibodies
 

PROTEIN VIEW

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ACADSB-001
 
ACADSB-002
 
ACADSB-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACADSB-001 ENSP00000357873
ENST00000358776
P45954
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Show » Show » 432 47.5 No 0
ACADSB-002 ENSP00000407744
ENST00000411816
Show » 171 18.8 No 0
ACADSB-004 ENSP00000357862
ENST00000368869
B4DQ51
Show all »
Show » Show » 330 36 No 0