CGB7

GENERAL INFORMATION

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Gene name

CGB7

Gene description

Chorionic gonadotropin, beta polypeptide 7

Protein class

Cancer-related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (placenta, skin)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Selective cytoplasmic expression in placenta.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Caution, targets protein from more than one gene. External characterization data supports antibody staining.

Data reliability

Supportive based on 2 antibodies.
HPA038925 , HPA038934
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (placenta, skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

CGB7 (HGNC Symbol)

Synonyms

CG-beta-a

Description

Chorionic gonadotropin, beta polypeptide 7 (HGNC Symbol)

Entrez gene summary

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49054275 - 49058860

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196337 (version 78.38)

Entrez gene

94027

UniProt

P01233 (UniProt - Evidence at protein level)

neXtProt

NX_P01233

Antibodypedia

CGB7 antibodies


PROTEIN BROWSER

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ENST00000377280
 
ENST00000596965
 
ENST00000597853
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CGB7-001 ENSP00000469076
ENST00000596965
P01233
Show all »
Show » Show » 165 17.8 Yes 0
CGB7-002 ENSP00000470813
ENST00000597853
P01233
Show all »
Show » Show » 165 17.8 Yes 0
CGB7-201 ENSP00000366493
ENST00000377280
P01233
Show all »
Show » Show » 165 17.8 Yes 0