ADH7

GENE INFORMATION

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Gene name

ADH7 (HGNC Symbol)

Synonyms

ADH-4

Description

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (HGNC Symbol)

Entrez gene summary

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Chromosome

4 (Chromosome progress)

Cytoband

q23

Chromosome location (bp)

100333418 - 100356894

Ensembl

ENSG00000196344 (version 73.37)

Entrez gene

131

UniProt

P40394 (UniProt - Evidence at protein level)

neXtProt

NX_P40394

Antibodypedia

ADH7 antibodies
 

PROTEIN VIEW

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ADH7-001
 
ADH7-002
 
ADH7-003
 
ADH7-004
 
ADH7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADH7-001 ENSP00000414254
ENST00000437033
P40394
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Show » Show » 374 40 No 0
ADH7-002 ENSP00000420269
ENST00000476959
P40394
Show all »
Show » Show » 394 42.5 No 0
ADH7-003 ENSP00000420613
ENST00000482593
E9PFG0
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Show » Show » 317 33.7 No 0
ADH7-004 ENSP00000420300
ENST00000474027
C9JP14
Show all »
Show » 108 11.6 No 0
ADH7-201 ENSP00000209665
ENST00000209665
P40394
Show all »
Show » Show » 386 41.5 No 0