CD55

GENE INFORMATION

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Gene name

CD55 (HGNC Symbol)

Synonyms

CR, CROM, DAF, TC

Description

CD55 molecule, decay accelerating factor for complement (Cromer blood group) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q32.2

Chromosome location (bp)

207494853 - 207534311

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196352 (version 75.37)

Entrez gene

1604

UniProt

P08174 (UniProt - Evidence at protein level)

neXtProt

NX_P08174

Antibodypedia

CD55 antibodies
 

PROTEIN VIEW

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CD55-001
 
CD55-002
 
CD55-003
 
CD55-007
 
CD55-008
 
CD55-009
 
CD55-201
 
CD55-202
 
CD55-203
 
CD55-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD55-001 ENSP00000356031
ENST00000367064
P08174
Show all »
Show » Show » 381 41.4 Yes 1
CD55-002 ENSP00000375788
ENST00000391921
B1AP15
Show all »
Show » 317 34 Yes 1
CD55-003 ENSP00000356030
ENST00000367063
B1AP13
Show all »
Show » 444 49.3 Yes 0
CD55-007 ENSP00000433984
ENST00000482390
E9PSH2
Show all »
Show » 377 41.2 Yes 0
CD55-008 ENSP00000340631
ENST00000343420
Show » 326 35.7 Yes 0
CD55-009 ENSP00000316333
ENST00000314754
P08174
Show all »
Show » Show » 440 48.7 Yes 0
CD55-201 ENSP00000356029
ENST00000367062
P08174
Show all »
Show » Show » 364 39.8 Yes 0
CD55-202 ENSP00000356032
ENST00000367065
P08174
Show all »
Show » Show » 439 48.5 Yes 0
CD55-203 ENSP00000356034
ENST00000367067
H7BY55
Show all »
Show » 129 14.3 Yes 0
CD55-204 ENSP00000375787
ENST00000391920
P08174
Show all »
Show » Show » 384 41.9 Yes 0