HSH2D

GENE INFORMATION

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Gene name

HSH2D (HGNC Symbol)

Synonyms

ALX, FLJ14886, HSH2

Description

Hematopoietic SH2 domain containing (HGNC Symbol)

Entrez gene summary

T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

16244838 - 16269386

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000196684 (version 75.37)

Entrez gene

84941

UniProt

Q96JZ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q96JZ2

Antibodypedia

HSH2D antibodies
 

PROTEIN VIEW

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HSH2D-001
 
HSH2D-002
 
HSH2D-003
 
HSH2D-004
 
HSH2D-005
 
HSH2D-007
 
HSH2D-008
 
HSH2D-009
 
HSH2D-201
 
HSH2D-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSH2D-001 ENSP00000468268
ENST00000588246
K7ERI2
Show all »
Show » Show » 300 33.7 No 0
HSH2D-002 ENSP00000467576
ENST00000589463
K7EPX4
Show all »
Show » 69 7.6 No 0
HSH2D-003 ENSP00000442140
ENST00000535834
B4DT26
Show all »
Show » 162 17.6 No 0
HSH2D-004 ENSP00000465636
ENST00000587963
K7EKI5
Show all »
Show » Show » 85 9.4 No 0
HSH2D-005 ENSP00000468495
ENST00000586872
K7ES08
Show all »
Show » Show » 72 8.1 No 0
HSH2D-007 ENSP00000467189
ENST00000593031
K7EP18
Show all »
Show » Show » 173 19.2 No 0
HSH2D-008 ENSP00000468142
ENST00000591154
Show » 40 4.3 No 0
HSH2D-009 ENSP00000464833
ENST00000593154
K7ERI2
Show all »
Show » Show » 300 33.7 No 0
HSH2D-201 ENSP00000253680
ENST00000253680
Q96JZ2
Show all »
Show » Show » 352 39 No 0
HSH2D-202 ENSP00000380528
ENST00000397372
H7BYQ7
Show all »
Show » 262 29 No 0