CD47

GENE INFORMATION

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Gene name

CD47 (HGNC Symbol)

Synonyms

IAP, MER6, OA3

Description

CD47 molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

Chromosome

3 (Chromosome progress)

Cytoband

q13.12

Chromosome location (bp)

107762145 - 107809872

Ensembl

ENSG00000196776 (version 73.37)

Entrez gene

961

UniProt

Q08722 (UniProt - Evidence at protein level)

neXtProt

NX_Q08722

Antibodypedia

CD47 antibodies
 

PROTEIN VIEW

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CD47-001
 
CD47-002
 
CD47-004
 
CD47-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD47-001 ENSP00000381309
ENST00000398258
86 9.9 No 0
CD47-002 ENSP00000347512
ENST00000355354
Q08722
Show all »
Show » Show » 305 33.2 Yes 5
CD47-004 ENSP00000355361
ENST00000361309
Q08722
Show all »
Show » Show » 323 35.2 Yes 6
CD47-005 ENSP00000430843
ENST00000517766
Show » 109 11.4 No 4