ADA

GENE INFORMATION

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Gene name

ADA

Synonyms

Description

adenosine deaminase (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q13.12

Chromosome location (bp)

43248163 - 43280874

Ensembl

ENSG00000196839 (version 73.37)

Entrez gene

100

UniProt

P00813 (UniProt - Evidence at protein level)

neXtProt

NX_P00813

Antibodypedia

ADA antibodies
 

PROTEIN VIEW

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ADA-001
 
ADA-004
 
ADA-007
 
ADA-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADA-001 ENSP00000361965
ENST00000372874
P00813
Show all »
Show » Show » 363 40.8 No 0
ADA-004 ENSP00000440946
ENST00000536532
F5GXW0
Show all »
Show » 263 29.3 No 0
ADA-007 ENSP00000446464
ENST00000539235
F5GYD4
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Show » 75 8.4 No 0
ADA-008 ENSP00000441818
ENST00000537820
F5GWI4
Show all »
Show » 339 38.3 No 0