SCN8A

TISSUE ATLAS

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Gene description

Sodium channel, voltage gated, type VIII, alpha subunit

RNA tissue category

Group enriched (cerebral cortex, testis).

Protein summary

Detected at High or Medium expression level in 19 of 77 analyzed normal tissue cell types.

Protein expression

Strong membranous staining was observed in the superficial layers of squamous epithelia. The gastrointestinal tract and gall bladder showed moderate membranous staining while renal tubuli and urinary bladder displayed membranous cytoplasmic staining. Remaining normal cells were weakly stained or negative.

Protein class

Potential transmembrane proteins, Transporters, Voltage-gated ion channels

Protein evidence

Medium

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Esophagus
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

20
10
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle N/A
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland N/A
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

CAB022169