PDLIM7

GENE INFORMATION

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Gene name

PDLIM7 (HGNC Symbol)

Synonyms

ENIGMA

Description

PDZ and LIM domain 7 (enigma) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q35.3

Chromosome location (bp)

176910395 - 176924607

Ensembl

ENSG00000196923 (version 73.37)

Entrez gene

9260

UniProt

Q9NR12 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NR12

Antibodypedia

PDLIM7 antibodies
 

PROTEIN VIEW

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PDLIM7-001
 
PDLIM7-002
 
PDLIM7-003
 
PDLIM7-004
 
PDLIM7-006
 
PDLIM7-007
 
PDLIM7-009
 
PDLIM7-010
 
PDLIM7-012
 
PDLIM7-013
 
PDLIM7-015
 
PDLIM7-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDLIM7-001 ENSP00000348099
ENST00000355841
Q9NR12
Show all »
Show » 457 49.8 No 0
PDLIM7-002 ENSP00000431236
ENST00000493815
Q9NR12
Show all »
Show » 153 16 No 0
PDLIM7-003 ENSP00000352964
ENST00000359895
Q9NR12
Show all »
Show » 423 46.5 No 0
PDLIM7-004 ENSP00000347776
ENST00000355572
Q9NR12
Show all »
Show » 222 24.4 No 0
PDLIM7-006 ENSP00000439157
ENST00000486828
Q9NR12
Show all »
Show » 191 20.5 No 0
PDLIM7-007 ENSP00000377182
ENST00000393551
Q9NR12
Show all »
Show » 287 30.4 No 0
PDLIM7-009 ENSP00000424850
ENST00000506161
D6RF83
Show all »
Show » 173 18.5 No 0
PDLIM7-010 ENSP00000421664
ENST00000506537
D6RAN1
Show all »
Show » 90 9.5 No 0
PDLIM7-012 ENSP00000377177
ENST00000393546
H7BYK4
Show all »
Show » 195 20.6 No 0
PDLIM7-013 ENSP00000422363
ENST00000503827
Show » 120 12.6 No 0
PDLIM7-015 ENSP00000426213
ENST00000505074
D6RH06
Show all »
Show » 287 30.6 No 0
PDLIM7-201 ENSP00000349030
ENST00000356618
Q9NR12
Show all »
Show » 287 30.4 No 0