SLC6A17

GENERAL INFORMATION

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Gene name

SLC6A17

Gene description

Solute carrier family 6 (neutral amino acid transporter), member 17

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (cerebellum, cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in CNS.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA007663 , HPA008044
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Hippocampus

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum, cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

SLC6A17

Synonyms

Description

Solute carrier family 6 (neutral amino acid transporter), member 17 (HGNC Symbol)

Entrez gene summary

The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008]

Chromosome

1

Cytoband

p13.3

Chromosome location (bp)

110150486 - 110202202

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197106 (version 78.38)

Entrez gene

388662

UniProt

Q9H1V8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H1V8

Antibodypedia

SLC6A17 antibodies


PROTEIN BROWSER

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ENST00000331565
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC6A17-001 ENSP00000330199
ENST00000331565
Q9H1V8
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