ACSL5

GENE INFORMATION

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Gene name

ACSL5 (HGNC Symbol)

Synonyms

ACS2, ACS5, FACL5

Description

acyl-CoA synthetase long-chain family member 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q25.2

Chromosome location (bp)

114133776 - 114188138

Ensembl

ENSG00000197142 (version 73.37)

Entrez gene

51703

UniProt

Q9ULC5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULC5

Antibodypedia

ACSL5 antibodies
 

PROTEIN VIEW

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ACSL5-001
 
ACSL5-002
 
ACSL5-201
 
ACSL5-202
 
ACSL5-203
 
ACSL5-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACSL5-001 ENSP00000346223
ENST00000354273
Q9ULC5
Show all »
Show » Show » 683 76 No 3
ACSL5-002 ENSP00000346680
ENST00000354655
Q9ULC5
Show all »
Show » Show » 683 76 No 3
ACSL5-201 ENSP00000348429
ENST00000356116
Q9ULC5
Show all »
Show » Show » 739 82.3 No 4
ACSL5-202 ENSP00000358418
ENST00000369410
B4DX30
Show all »
Show » Show » 465 51.7 No 0
ACSL5-203 ENSP00000376796
ENST00000393081
Q9ULC5
Show all »
Show » Show » 683 76 No 3
ACSL5-204 ENSP00000403647
ENST00000433418
Q9ULC5
Show all »
Show » Show » 659 73.3 No 3