SERPINA1

GENE INFORMATION

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Gene name

SERPINA1 (HGNC Symbol)

Synonyms

A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1

Description

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

14 (Chromosome progress)

Cytoband

q32.13

Chromosome location (bp)

94843084 - 94857030

Ensembl

ENSG00000197249 (version 73.37)

Entrez gene

5265

UniProt

P01009 (UniProt - Evidence at protein level)

neXtProt

NX_P01009

Antibodypedia

SERPINA1 antibodies
 

PROTEIN VIEW

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 « 
 
SERPINA1-001
 
SERPINA1-002
 
SERPINA1-003
 
SERPINA1-004
 
SERPINA1-005
 
SERPINA1-006
 
SERPINA1-007
 
SERPINA1-008
 
SERPINA1-010
 
SERPINA1-011
 
SERPINA1-015
 
SERPINA1-016
 
SERPINA1-017
 
SERPINA1-201
 
SERPINA1-202
 
SERPINA1-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINA1-001 ENSP00000390299
ENST00000440909
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-002 ENSP00000376803
ENST00000393088
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-003 ENSP00000385960
ENST00000404814
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-004 ENSP00000376802
ENST00000393087
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-005 ENSP00000451525
ENST00000489769
P01009
Show all »
Show » Show » 306 34.8 Yes 0
SERPINA1-006 ENSP00000386094
ENST00000402629
P01009
Show all »
Show » Show » 359 40.3 Yes 0
SERPINA1-007 ENSP00000452452
ENST00000557492
G3V387
Show all »
Show » Show » 144 15.7 Yes 0
SERPINA1-008 ENSP00000416354
ENST00000449399
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-010 ENSP00000451826
ENST00000557118
G3V4I7
Show all »
Show » 22 2.2 Yes 0
SERPINA1-011 ENSP00000451098
ENST00000556955
G3V387
Show all »
Show » Show » 117 12.7 Yes 0
SERPINA1-015 ENSP00000452480
ENST00000553327
G3V5R8
Show all »
Show » Show » 92 9.9 Yes 0
SERPINA1-016 ENSP00000450561
ENST00000554720
G3V2B9
Show all »
Show » 105 11.8 No 0
SERPINA1-017 ENSP00000452169
ENST00000556091
G3V544
Show all »
Show » Show » 156 17.1 Yes 0
SERPINA1-201 ENSP00000348068
ENST00000355814
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-202 ENSP00000408474
ENST00000437397
P01009
Show all »
Show » Show » 418 46.7 Yes 0
SERPINA1-203 ENSP00000416066
ENST00000448921
P01009
Show all »
Show » Show » 418 46.7 Yes 0