SYNGAP1

GENE INFORMATION

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Gene name

SYNGAP1 (HGNC Symbol)

Synonyms

KIAA1938, RASA5, SYNGAP

Description

Synaptic Ras GTPase activating protein 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5). [provided by RefSeq, Dec 2009]

Chromosome

6

Cytoband

p21.32

Chromosome location (bp)

33387847 - 33421466

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197283 (version 75.37)

Entrez gene

8831

UniProt

Q96PV0 (UniProt - Evidence at protein level)

neXtProt

NX_Q96PV0

Antibodypedia

SYNGAP1 antibodies
 

PROTEIN VIEW

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SYNGAP1-001
 
SYNGAP1-003
 
SYNGAP1-009
 
SYNGAP1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYNGAP1-001 ENSP00000403636
ENST00000418600
Q96PV0
Show all »
Show » Show » 1343 148.3 No 0
SYNGAP1-003 ENSP00000412475
ENST00000428982
Q96PV0
Show all »
Show » Show » 1284 140.9 No 0
SYNGAP1-009 ENSP00000416519
ENST00000449372
B7ZCA0
Show all »
Show » Show » 1279 141.3 No 0
SYNGAP1-201 ENSP00000293748
ENST00000293748
Q96PV0
Show all »
Show » Show » 1299 143.6 No 0