Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Plasma membrane, Cytoplasm

Additional location(s)

 

Staining summary

Localized to the cytoplasm and plasma membrane.

Reliability (APE)

Medium

Antibodies in assay

CAB002720, HPA014520
 

Antibody CAB002720

 

Antibody HPA014520

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Plasma membrane, Cytoplasm  

Staining characteristics

  

Staining intensity

Moderate Negative 

Validation

Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

  

Staining characteristics

  

Staining intensity

Negative Negative 

Validation

No staining.
 
No staining.
 

Comment

  

         Cell line U-251 MG

Toggle channels

 
 

Location(s)

  

Staining characteristics

  

Staining intensity

Negative Negative 

Validation

No staining.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in plasma membrane & cytoplasm.
 

Immunofluorescent staining of human cell line U-251MG shows no positivity.
 

Summary

Staining of the plasma membrane and cytoplasm in A-431.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Plasma membrane