GZMM

GENE INFORMATION

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Gene name

GZMM (HGNC Symbol)

Synonyms

LMET1, MET1

Description

granzyme M (lymphocyte met-ase 1) (HGNC Symbol)

Entrez gene summary

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Chromosome

19 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

544034 - 549919

Ensembl

ENSG00000197540 (version 73.37)

Entrez gene

3004

UniProt

P51124 (UniProt - Evidence at protein level)

neXtProt

NX_P51124

Antibodypedia

GZMM antibodies
 

PROTEIN VIEW

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GZMM-001
 
GZMM-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GZMM-001 ENSP00000264553
ENST00000264553
P51124
Show all »
Show » Show » 257 27.5 Yes 0
GZMM-002 ENSP00000476255
ENST00000592501
Show » Show » 250 26.5 No 0