TOPORS

GENE INFORMATION

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Gene name

TOPORS (HGNC Symbol)

Synonyms

LUN, RP31, TP53BPL

Description

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus. [provided by RefSeq, Sep 2010]

Chromosome

9 (Chromosome progress)

Cytoband

p21.1

Chromosome location (bp)

32540542 - 32552551

Ensembl

ENSG00000197579 (version 73.37)

Entrez gene

10210

UniProt

Q9NS56 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NS56

Antibodypedia

TOPORS antibodies
 

PROTEIN VIEW

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TOPORS-001
 
TOPORS-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TOPORS-001 ENSP00000353735
ENST00000360538
Q9NS56
Show all »
Show » 1045 119.2 No 0
TOPORS-002 ENSP00000369187
ENST00000379858
Q9NS56
Show all »
Show » 980 112.3 No 0