KCNMB2

GENE INFORMATION

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Gene name

KCNMB2

Synonyms

Description

potassium large conductance calcium-activated channel, subfamily M, beta member 2 (HGNC Symbol)

Entrez gene summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013]

Chromosome

3 (Chromosome progress)

Cytoband

q26.32

Chromosome location (bp)

177990720 - 178562217

Ensembl

ENSG00000197584 (version 73.37)

Entrez gene

10242

UniProt

Q9Y691 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y691

Antibodypedia

KCNMB2 antibodies
 

PROTEIN VIEW

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KCNMB2-001
 
KCNMB2-002
 
KCNMB2-003
 
KCNMB2-004
 
KCNMB2-012
 
KCNMB2-013
 
KCNMB2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNMB2-001 ENSP00000397483
ENST00000452583
Q9Y691
Show all »
Show » Show » 235 27.1 No 2
KCNMB2-002 ENSP00000395807
ENST00000437510
E7ETM2
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Show » Show » 137 15.8 No 1
KCNMB2-003 ENSP00000407592
ENST00000432997
Q9Y691
Show all »
Show » Show » 235 27.1 No 2
KCNMB2-004 ENSP00000408252
ENST00000420517
Q9Y691
Show all »
Show » Show » 235 27.1 No 2
KCNMB2-012 ENSP00000399100
ENST00000455865
E7EM81
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Show » Show » 100 11.6 No 1
KCNMB2-013 ENSP00000414228
ENST00000422927
F8WE19
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26 3 No 0
KCNMB2-201 ENSP00000351068
ENST00000358316
Q9Y691
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Show » Show » 235 27.1 No 2