HIST4H4

GENE INFORMATION

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Gene name

HIST4H4 (HGNC Symbol)

Synonyms

MGC24116

Description

Histone cluster 4, H4 (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p12.3

Chromosome location (bp)

14920933 - 14924065

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000197837 (version 75.37)

Entrez gene

554313

UniProt

P62805 (UniProt - Evidence at protein level)

neXtProt

NX_P62805

Antibodypedia

HIST4H4 antibodies
 

PROTEIN VIEW

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HIST4H4-001
 
HIST4H4-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HIST4H4-001 ENSP00000350767
ENST00000358064
P62805
Show all »
Show » Show » 103 11.4 No 0
HIST4H4-002 ENSP00000443017
ENST00000539745
P62805
Show all »
Show » Show » 103 11.4 No 0