ADH5

GENE INFORMATION

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Gene name

ADH5 (HGNC Symbol)

Synonyms

ADH-3, ADHX, FDH

Description

alcohol dehydrogenase 5 (class III), chi polypeptide (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q23

Chromosome location (bp)

99992132 - 100009952

Ensembl

ENSG00000197894 (version 73.37)

Entrez gene

128

UniProt

P11766 (UniProt - Evidence at protein level)

neXtProt

NX_P11766

Antibodypedia

ADH5 antibodies
 

PROTEIN VIEW

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ADH5-001
 
ADH5-005
 
ADH5-006
 
ADH5-009
 
ADH5-011
 
ADH5-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADH5-001 ENSP00000296412
ENST00000296412
P11766
Show all »
Show » Show » 374 39.7 No 0
ADH5-005 ENSP00000421556
ENST00000505652
D6RFE4
Show all »
Show » 115 12.2 No 0
ADH5-006 ENSP00000427026
ENST00000502386
15 1.7 No 0
ADH5-009 ENSP00000422119
ENST00000502590
D6R9G2
Show all »
Show » 95 10.1 No 0
ADH5-011 ENSP00000427049
ENST00000503130
H0YAG8
Show all »
Show » Show » 262 27.5 No 0
ADH5-013 ENSP00000424650
ENST00000512659
D6RAY0
Show all »
Show » 56 6.1 No 0