AVPR1B

GENE INFORMATION

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Gene name

AVPR1B (HGNC Symbol)

Synonyms

AVPR3

Description

arginine vasopressin receptor 1B (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q32.1

Chromosome location (bp)

206223976 - 206231639

Ensembl

ENSG00000198049 (version 73.37)

Entrez gene

553

UniProt

P47901 (UniProt - Evidence at transcript level)

neXtProt

NX_P47901

Antibodypedia

AVPR1B antibodies
 

PROTEIN VIEW

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AVPR1B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AVPR1B-001 ENSP00000356094
ENST00000367126
P47901
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