LPAR1

GENE INFORMATION

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Gene name

LPAR1 (HGNC Symbol)

Synonyms

edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1

Description

lysophosphatidic acid receptor 1 (HGNC Symbol)

Entrez gene summary

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q31.3

Chromosome location (bp)

113635543 - 113800981

Ensembl

ENSG00000198121 (version 73.37)

Entrez gene

1902

UniProt

Q92633 (UniProt - Evidence at protein level)

neXtProt

NX_Q92633

Antibodypedia

LPAR1 antibodies
 

PROTEIN VIEW

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LPAR1-001
 
LPAR1-002
 
LPAR1-003
 
LPAR1-004
 
LPAR1-201
 
LPAR1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LPAR1-001 ENSP00000363553
ENST00000374431
Q92633
Show all »
Show » Show » 364 41.1 No 7
LPAR1-002 ENSP00000363552
ENST00000374430
Q92633
Show all »
Show » Show » 364 41.1 No 7
LPAR1-003 ENSP00000351755
ENST00000358883
Q92633
Show all »
Show » Show » 364 41.1 No 7
LPAR1-004 ENSP00000401810
ENST00000441240
B1AP63
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Show » Show » 182 20.6 No 4
LPAR1-201 ENSP00000440201
ENST00000538760
B4DQ18
Show all »
Show » Show » 365 41.2 No 7
LPAR1-202 ENSP00000445697
ENST00000541779
B4DK36
Show all »
Show » Show » 365 41.3 No 7