CACNA1E

GENE INFORMATION

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Gene name

CACNA1E (HGNC Symbol)

Synonyms

BII, CACH6, CACNL1A6, Cav2.3

Description

calcium channel, voltage-dependent, R type, alpha 1E subunit (HGNC Symbol)

Entrez gene summary

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]

Chromosome

1 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

181382238 - 181777219

Ensembl

ENSG00000198216 (version 73.37)

Entrez gene

777

UniProt

Q15878 (UniProt - Evidence at protein level)

neXtProt

NX_Q15878

Antibodypedia

CACNA1E antibodies
 

PROTEIN VIEW

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CACNA1E-001
 
CACNA1E-002
 
CACNA1E-003
 
CACNA1E-004
 
CACNA1E-006
 
CACNA1E-201
 
CACNA1E-202
 
CACNA1E-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CACNA1E-001 ENSP00000356542
ENST00000367570
Q15878
Show all »
Show » Show » 2270 257.1 No >9
CACNA1E-002 ENSP00000434814
ENST00000526775
Q15878
Show all »
Show » Show » 2251 254.6 No >9
CACNA1E-003 ENSP00000356545
ENST00000367573
Q15878
Show all »
Show » Show » 2313 261.7 No >9
CACNA1E-004 ENSP00000432038
ENST00000524607
E9PIE8
Show all »
Show » Show » 438 49.3 No 6
CACNA1E-006 ENSP00000353222
ENST00000360108
F8W9Z1
Show all »
Show » Show » 2294 259.2 No >9
CACNA1E-201 ENSP00000350183
ENST00000357570
J3KP11
Show all »
Show » Show » 2264 256.7 No >9
CACNA1E-202 ENSP00000351101
ENST00000358338
F8W8A2
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Show » Show » 2202 249.6 No >9
CACNA1E-203 ENSP00000356539
ENST00000367567
F8W760
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Show » Show » 1877 212.9 No >9