CARD11

GENE INFORMATION

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Gene name

CARD11 (HGNC Symbol)

Synonyms

BIMP3, CARMA1

Description

caspase recruitment domain family, member 11 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

2945775 - 3083579

Ensembl

ENSG00000198286 (version 73.37)

Entrez gene

84433

UniProt

Q9BXL7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXL7

Antibodypedia

CARD11 antibodies
 

PROTEIN VIEW

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CARD11-011
 
CARD11-012
 
CARD11-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CARD11-011 ENSP00000380150
ENST00000396946
Q9BXL7
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Show » Show » 1154 133.3 No 0
CARD11-012 ENSP00000348779
ENST00000356408
E2QRC0
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Show » Show » 73 8.5 No 0
CARD11-013 ENSP00000347695
ENST00000355508
H7BY05
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Show » Show » 272 29.7 No 0