Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Nucleus, Cytoplasm

Additional location(s)

Nucleoli 

Staining summary

Localized to the nucleus and cytoplasm.

Reliability (APE)

High

Antibodies in assay

HPA001395, CAB004607, CAB015834
 

Antibody HPA001395

 

Antibody CAB004607

 

Antibody CAB015834

 

         Cell line A-431

Toggle channels

 
 
 

Location(s)

Nucleus, Nucleoli, Cytoplasm  Nucleus 

Staining characteristics

Granular   

Staining intensity

Weak Negative Weak 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
No staining.
 
One/multiple location(s) supported by experimental gene/protein characterization data.
 

Comment

   

         Cell line U-2 OS

Toggle channels

 
   

Location(s)

Cytoplasm    

Staining characteristics

Granular    

Staining intensity

Weak Negative   

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
No staining.
   

Comment

    

         Cell line U-251 MG

Toggle channels

 
   

Location(s)

Cytoplasm    

Staining characteristics

Smooth    

Staining intensity

Weak Negative   

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
No staining.
   

Comment

    

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in cytoplasm.
 

Immunofluorescent staining of human cell line A-431 shows no positivity.
 

Immunofluorescent staining of human cell line A-431 shows positivity in nucleus.
 

Summary

Staining of cytoplasm in all three cell lines with additional staining of nucleus and nucleoli in A-431.   No staining was observed in any of the three cell lines.   Staining of nucleus in A-431.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is supported by literature.
 

Dictionary

Cytoplasm
Nucleoli
Nucleus