CNGA1

GENE INFORMATION

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Gene name

CNGA1 (HGNC Symbol)

Synonyms

CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49

Description

cyclic nucleotide gated channel alpha 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p12

Chromosome location (bp)

47937994 - 48018689

Ensembl

ENSG00000198515 (version 73.37)

Entrez gene

1259

UniProt

P29973 (UniProt - Evidence at protein level)

neXtProt

NX_P29973

Antibodypedia

CNGA1 antibodies
 

PROTEIN VIEW

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CNGA1-001
 
CNGA1-005
 
CNGA1-006
 
CNGA1-007
 
CNGA1-008
 
CNGA1-009
 
CNGA1-201
 
CNGA1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNGA1-001 ENSP00000384264
ENST00000402813
P29973
Show all »
Show » Show » 759 86.9 No 5
CNGA1-005 ENSP00000423327
ENST00000513178
D6R978
Show all »
Show » 99 11 No 0
CNGA1-006 ENSP00000426862
ENST00000514170
P29973
Show all »
Show » Show » 690 79.6 No 5
CNGA1-007 ENSP00000389881
ENST00000420489
P29973
Show all »
Show » Show » 690 79.6 No 5
CNGA1-008 ENSP00000423721
ENST00000504722
D6RCF1
Show all »
Show » 128 14.5 No 0
CNGA1-009 ENSP00000421110
ENST00000514520
D6R978
Show all »
Show » 99 11 No 0
CNGA1-201 ENSP00000351320
ENST00000358519
P29973
Show all »
Show » Show » 690 79.6 No 5
CNGA1-202 ENSP00000443401
ENST00000544810
P29973
Show all »
Show » Show » 690 79.6 No 5