MAGEA1

GENERAL INFORMATION

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Gene name

MAGEA1

Gene description

Melanoma antigen family A, 1 (directs expression of antigen MZ2-E)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Nuclear and cytoplasmic staining of spermatogonia in seminiferus ducts in testis.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
CAB002620
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

MAGEA1 (HGNC Symbol)

Synonyms

CT1.1, MAGE1, MGC9326

Description

Melanoma antigen family A, 1 (directs expression of antigen MZ2-E) (HGNC Symbol)

Entrez gene summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

153179285 - 153183880

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198681 (version 78.38)

Entrez gene

4100

UniProt

P43355 (UniProt - Evidence at protein level)

neXtProt

NX_P43355

Antibodypedia

MAGEA1 antibodies


PROTEIN BROWSER

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ENST00000356661
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAGEA1-001 ENSP00000349085
ENST00000356661
P43355
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