MTOR

GENE INFORMATION

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Gene name

MTOR (HGNC Symbol)

Synonyms

FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1

Description

mechanistic target of rapamycin (serine/threonine kinase) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p36.22

Chromosome location (bp)

11166592 - 11322564

Ensembl

ENSG00000198793 (version 73.37)

Entrez gene

2475

UniProt

P42345 (UniProt - Evidence at protein level)

neXtProt

NX_P42345

Antibodypedia

MTOR antibodies
 

PROTEIN VIEW

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MTOR-001
 
MTOR-002
 
MTOR-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MTOR-001 ENSP00000354558
ENST00000361445
P42345
Show all »
Show » Show » 2549 288.9 No 0
MTOR-002 ENSP00000366034
ENST00000376838
B1AKP8
Show all »
Show » 754 85.9 No 0
MTOR-005 ENSP00000398745
ENST00000455339
B1AKQ2
Show all »
Show » 161 18.2 No 0