TOP1

GENE INFORMATION

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Gene name

TOP1

Synonyms

Description

topoisomerase (DNA) I (HGNC Symbol)

Entrez gene summary

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

39657458 - 39753127

Ensembl

ENSG00000198900 (version 73.37)

Entrez gene

7150

UniProt

P11387 (UniProt - Evidence at protein level)

neXtProt

NX_P11387

Antibodypedia

TOP1 antibodies
 

PROTEIN VIEW

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TOP1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TOP1-001 ENSP00000354522
ENST00000361337
P11387
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