NOS1AP

GENE INFORMATION

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Gene name

NOS1AP (HGNC Symbol)

Synonyms

CAPON, KIAA0464

Description

nitric oxide synthase 1 (neuronal) adaptor protein (HGNC Symbol)

Entrez gene summary

This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009]

Chromosome

1 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

162039564 - 162353321

Ensembl

ENSG00000198929 (version 73.37)

Entrez gene

9722

UniProt

O75052 (UniProt - Evidence at protein level)

neXtProt

NX_O75052

Antibodypedia

NOS1AP antibodies
 

PROTEIN VIEW

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NOS1AP-001
 
NOS1AP-002
 
NOS1AP-005
 
NOS1AP-007
 
NOS1AP-008
 
NOS1AP-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NOS1AP-001 ENSP00000355133
ENST00000361897
O75052
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Show » 506 56.1 No 0
NOS1AP-002 ENSP00000435711
ENST00000464284
E9PIP8
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81 8.6 No 0
NOS1AP-005 ENSP00000356909
ENST00000367932
H7BY61
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51 5.9 No 0
NOS1AP-007 ENSP00000434988
ENST00000493151
O75052
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Show » 211 23 Yes 0
NOS1AP-008 ENSP00000431586
ENST00000530878
O75052
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Show » 501 55.6 No 0
NOS1AP-009 ENSP00000396713
ENST00000430120
E9PSG0
Show all »
Show » Show » 349 38.8 No 1