SGMS1

GENERAL INFORMATION

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Gene name

SGMS1

Gene description

Sphingomyelin synthase 1

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression, most abundant in squamous epithelia.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA045191
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Oral mucosa

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SGMS1 (HGNC Symbol)

Synonyms

MGC17342, MOB, SMS1, TMEM23

Description

Sphingomyelin synthase 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is predicted to be a five-pass transmembrane protein. This gene may be predominately expressed in brain. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q11.23

Chromosome location (bp)

50305586 - 50625163

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000198964 (version 78.38)

Entrez gene

259230

UniProt

Q86VZ5 (UniProt - Evidence at protein level)

neXtProt

NX_Q86VZ5

Antibodypedia

SGMS1 antibodies


PROTEIN BROWSER

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ENST00000361543
 
ENST00000361781
 
ENST00000429490
 
ENST00000602565
 
ENST00000602619
 
ENST00000619438
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SGMS1-002 ENSP00000475427
ENST00000602565
Show » 12 1.6 No 0
SGMS1-003 ENSP00000354829
ENST00000361781
Q86VZ5
Show all »
Show » Show » 413 48.6 No 6
SGMS1-005 ENSP00000473668
ENST00000602619
R4GNI5
Show all »
Show » 36 4.1 No 0
SGMS1-201 ENSP00000355235
ENST00000361543
C0MHM2
Show all »
Show » Show » 241 27.6 No 3
SGMS1-202 ENSP00000406795
ENST00000429490
E6ZCI6
Show all »
Show » Show » 219 25.3 No 2
SGMS1-203 ENSP00000479633
ENST00000619438
C0MHM2
Show all »
Show » Show » 241 27.6 No 3