AGER

GENE INFORMATION

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Gene name

AGER (HGNC Symbol)

Synonyms

RAGE

Description

advanced glycosylation end product-specific receptor (HGNC Symbol)

Entrez gene summary

The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]

Chromosome

6 (Chromosome progress)

Cytoband

p21.32

Chromosome location (bp)

32148745 - 32152101

Ensembl

ENSG00000204305 (version 73.37)

Entrez gene

177

UniProt

Q15109 (UniProt - Evidence at protein level)

neXtProt

NX_Q15109

Antibodypedia

AGER antibodies
 

PROTEIN VIEW

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AGER-001
 
AGER-002
 
AGER-004
 
AGER-007
 
AGER-008
 
AGER-201
 
AGER-202
 
AGER-203
 
AGER-204
 
AGER-205
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGER-001 ENSP00000364217
ENST00000375076
Q15109
Show all »
Show » Show » 404 42.8 Yes 1
AGER-002 ENSP00000364195
ENST00000375055
Q15109
Show all »
Show » Show » 347 37 Yes 0
AGER-004 ENSP00000364208
ENST00000375067
Q15109
Show all »
Show » Show » 342 36.2 Yes 0
AGER-007 ENSP00000364196
ENST00000375056
Q5SSZ2
Show all »
Show » Show » 233 25.2 Yes 0
AGER-008 ENSP00000398466
ENST00000450110
Q5SSZ3
Show all »
Show » Show » 234 25.2 Yes 0
AGER-201 ENSP00000364206
ENST00000375065
Q3L1R4
Show all »
Show » Show » 121 13.2 Yes 0
AGER-202 ENSP00000364210
ENST00000375069
A8MS87
Show all »
Show » Show » 294 31.3 No 1
AGER-203 ENSP00000364211
ENST00000375070
B4DNX3
Show all »
Show » Show » 435 46 No 1
AGER-204 ENSP00000387887
ENST00000438221
Q15109
Show all »
Show » Show » 363 39 Yes 0
AGER-205 ENSP00000445389
ENST00000538695
B5A982
Show all »
Show » Show » 128 14 Yes 0