PRRC2A

GENERAL INFORMATION

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Gene name

PRRC2A

Gene description

Proline-rich coiled-coil 2A

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA046791 , CAB026383
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PRRC2A (HGNC Symbol)

Synonyms

BAT2, D6S51E, G2

Description

Proline-rich coiled-coil 2A (HGNC Symbol)

Entrez gene summary

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

Chromosome

6

Cytoband

p21.33

Chromosome location (bp)

31620720 - 31637771

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204469 (version 78.38)

Entrez gene

7916

UniProt

P48634 (UniProt - Evidence at protein level)

neXtProt

NX_P48634

Antibodypedia

PRRC2A antibodies


PROTEIN BROWSER

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ENST00000376007
 
ENST00000376033
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRRC2A-001 ENSP00000365175
ENST00000376007
P48634
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Show » Show » 2157 228.9 No 0
PRRC2A-002 ENSP00000365201
ENST00000376033
P48634
Show all »
Show » Show » 2157 228.9 No 0