MRPS18B

GENE INFORMATION

? »

Gene name

MRPS18B (HGNC Symbol)

Synonyms

C6orf14, HSPC183, MRPS18-2, PTD017

Description

mitochondrial ribosomal protein S18B (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p21.33

Chromosome location (bp)

30585486 - 30594172

Ensembl

ENSG00000204568 (version 73.37)

Entrez gene

28973

UniProt

Q9Y676 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y676

Antibodypedia

MRPS18B antibodies
 

PROTEIN VIEW

? »
 
 
 
MRPS18B-001
 
MRPS18B-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS18B-001 ENSP00000259873
ENST00000259873
Q9Y676
Show all »
Show » Show » 258 29.4 No 0
MRPS18B-201 ENSP00000445207
ENST00000506373
B4DFG6
Show all »
Show » 121 14 No 0