ITSN1

GENE INFORMATION

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Gene name

ITSN1 (HGNC Symbol)

Synonyms

ITSN, MGC134948, MGC134949, SH3D1A, SH3P17

Description

intersectin 1 (SH3 domain protein) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008]

Chromosome

21 (Chromosome progress)

Cytoband

q22.11

Chromosome location (bp)

35014706 - 35272165

Ensembl

ENSG00000205726 (version 73.37)

Entrez gene

6453

UniProt

Q15811 (UniProt - Evidence at protein level)

neXtProt

NX_Q15811

Antibodypedia

ITSN1 antibodies
 

PROTEIN VIEW

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ITSN1-001
 
ITSN1-002
 
ITSN1-003
 
ITSN1-004
 
ITSN1-005
 
ITSN1-006
 
ITSN1-017
 
ITSN1-023
 
ITSN1-024
 
ITSN1-025
 
ITSN1-030
 
ITSN1-031
 
ITSN1-032
 
ITSN1-033
 
ITSN1-036
 
ITSN1-037
 
ITSN1-038
 
ITSN1-201
 
ITSN1-202
 
ITSN1-203
 
ITSN1-204
 
ITSN1-205
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITSN1-001 ENSP00000370719
ENST00000381318
Q15811
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Show » Show » 1721 195.4 No 0
ITSN1-002 ENSP00000370691
ENST00000381291
Q15811
Show all »
Show » Show » 1220 137.6 No 0
ITSN1-003 ENSP00000382286
ENST00000399349
Q15811
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Show » Show » 1144 129.4 No 0
ITSN1-004 ENSP00000370684
ENST00000381284
Q6J1T2
Show all »
Show » 317 36.2 No 0
ITSN1-005 ENSP00000409800
ENST00000415023
Q6J334
Show all »
Show » 173 19.8 No 0
ITSN1-006 ENSP00000413290
ENST00000437126
Q8IWU0
Show all »
Show » Show » 77 8.6 No 0
ITSN1-017 ENSP00000411464
ENST00000456489
60 6.3 No 0
ITSN1-023 ENSP00000382301
ENST00000399367
A8CTX8
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Show » Show » 1716 194.8 No 0
ITSN1-024 ENSP00000382289
ENST00000399352
B4DTM2
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Show » Show » 1215 137 No 0
ITSN1-025 ENSP00000382290
ENST00000399353
E7ERJ0
Show all »
Show » Show » 1178 133.6 No 0
ITSN1-030 ENSP00000396054
ENST00000440794
Q6J333
Show all »
Show » Show » 260 28.1 No 1
ITSN1-031 ENSP00000408319
ENST00000420666
Q6J1T1
Show all »
Show » 66 7.4 No 0
ITSN1-032 ENSP00000407132
ENST00000451686
C9JXS9
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Show » 78 8.8 No 0
ITSN1-033 ENSP00000400079
ENST00000444491
C9J1A4
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Show » 115 12.8 No 0
ITSN1-036 ENSP00000370683
ENST00000381283
C9JQZ7
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Show » 361 41 No 0
ITSN1-037 ENSP00000382292
ENST00000399355
F8W7U0
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Show » Show » 1149 130 No 0
ITSN1-038 ENSP00000415302
ENST00000419241
H7C429
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Show » Show » 77 8.6 No 0
ITSN1-201 ENSP00000369294
ENST00000379960
A8DCP3
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Show » Show » 914 104.2 No 0
ITSN1-202 ENSP00000370685
ENST00000381285
E9PD98
Show all »
Show » Show » 1721 195.4 No 0
ITSN1-203 ENSP00000382265
ENST00000399326
A7Y322
Show all »
Show » Show » 1015 115.5 No 0
ITSN1-204 ENSP00000382275
ENST00000399338
E7ERJ1
Show all »
Show » Show » 1020 115.9 No 1
ITSN1-205 ENSP00000387377
ENST00000437442
A8CTY3
Show all »
Show » Show » 1660 188.4 No 0