GAGE1

GENERAL INFORMATION

? »

Gene name

GAGE1

Gene description

G antigen 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Selective expression in spermatogonia.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 1 antibody.
HPA043232
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

? »

Gene name

GAGE1 (HGNC Symbol)

Synonyms

CT4.1

Description

G antigen 1 (HGNC Symbol)

Entrez gene summary

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Chromosome

X

Cytoband

p11.23

Chromosome location (bp)

49589496 - 49608536

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000205777 (version 78.38)

Entrez gene

2543

UniProt

Q13068 (UniProt - Evidence at protein level)

neXtProt

NX_Q13068

Antibodypedia

GAGE1 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000381700
 
ENST00000610680
 
ENST00000619375
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GAGE1-002 ENSP00000371119
ENST00000381700
Q13068
Show all »
Show » 117 12.9 No 0
GAGE1-201 ENSP00000482230
ENST00000610680
Q13068
Show all »
Show » 117 12.9 No 0
GAGE1-202 ENSP00000484668
ENST00000619375
Q13068
Show all »
Show » 117 12.9 No 0