DARC

GENE INFORMATION

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Gene name

DARC (HGNC Symbol)

Synonyms

ACKR1, CCBP1, CD234, Dfy, FY, GPD

Description

Duffy blood group, atypical chemokine receptor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.2

Chromosome location (bp)

159173097 - 159176290

Ensembl

ENSG00000213088 (version 73.37)

Entrez gene

2532

UniProt

Q16570 (UniProt - Evidence at protein level)

neXtProt

NX_Q16570

Antibodypedia

DARC antibodies
 

PROTEIN VIEW

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DARC-001
 
DARC-002
 
DARC-003
 
DARC-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DARC-001 ENSP00000357104
ENST00000368122
Q16570
Show all »
Show » Show » 336 35.6 No 7
DARC-002 ENSP00000357103
ENST00000368121
Q16570
Show all »
Show » Show » 338 35.7 No 7
DARC-003 ENSP00000398406
ENST00000435307
Q5JY94
Show all »
Show » Show » 155 16.4 No 3
DARC-201 ENSP00000441985
ENST00000537147
Q16570
Show all »
Show » Show » 336 35.6 No 7