MRPL23

GENE INFORMATION

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Gene name

MRPL23 (HGNC Symbol)

Synonyms

L23MRP, RPL23L

Description

mitochondrial ribosomal protein L23 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

p15.5

Chromosome location (bp)

1968508 - 2005752

Ensembl

ENSG00000214026 (version 73.37)

Entrez gene

6150

UniProt

Q16540 (UniProt - Evidence at protein level)

neXtProt

NX_Q16540

Antibodypedia

MRPL23 antibodies
 

PROTEIN VIEW

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MRPL23-001
 
MRPL23-002
 
MRPL23-003
 
MRPL23-007
 
MRPL23-009
 
MRPL23-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL23-001 ENSP00000380466
ENST00000397298
Q16540
Show all »
Show » Show » 153 17.8 No 0
MRPL23-002 ENSP00000370925
ENST00000381514
A6NJD9
Show all »
Show » 163 18.5 No 0
MRPL23-003 ENSP00000407156
ENST00000429295
Show » 118 13.7 No 0
MRPL23-007 ENSP00000370930
ENST00000381519
Q16540
Show all »
Show » Show » 153 17.8 No 0
MRPL23-009 ENSP00000380465
ENST00000397297
A8MYK1
Show all »
Show » 191 21.8 No 0
MRPL23-011 ENSP00000380462
ENST00000397294
A8MVT4
Show all »
Show » 166 18.8 No 0