MAGEB1

GENE INFORMATION

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Gene name

MAGEB1 (HGNC Symbol)

Synonyms

CT3.1, DAM10, MAGE-Xp, MAGEL1, MGC9322

Description

melanoma antigen family B, 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

p21.2

Chromosome location (bp)

30261847 - 30270155

Ensembl

ENSG00000214107 (version 73.37)

Entrez gene

4112

UniProt

P43366 (UniProt - Evidence at protein level)

neXtProt

NX_P43366

Antibodypedia

MAGEB1 antibodies
 

PROTEIN VIEW

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MAGEB1-001
 
MAGEB1-201
 
MAGEB1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAGEB1-001 ENSP00000368264
ENST00000378981
P43366
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Show » 347 39 No 0
MAGEB1-201 ENSP00000380681
ENST00000397548
P43366
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Show » 347 39 No 0
MAGEB1-202 ENSP00000380683
ENST00000397550
P43366
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Show » 347 39 No 0