SNURF

GENE INFORMATION

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Gene name

SNURF

Synonyms

Description

SNRPN upstream reading frame (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

25200133 - 25245423

Ensembl

ENSG00000214265 (version 73.37)

Entrez gene

6638

UniProt

Q9Y675 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y675

Antibodypedia

SNURF antibodies
 

PROTEIN VIEW

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SNURF-001
 
SNURF-002
 
SNURF-003
 
SNURF-005
 
SNURF-006
 
SNURF-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNURF-001 ENSP00000342152
ENST00000338327
Q9Y675
Show all »
Show » 71 8.4 No 0
SNURF-002 ENSP00000451421
ENST00000551312
Q9Y675
Show all »
Show » 71 8.4 No 0
SNURF-003 ENSP00000451898
ENST00000557230
G3V4N2
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Show » 37 4.5 No 0
SNURF-005 ENSP00000463201
ENST00000577949
Q9Y675
Show all »
Show » 71 8.4 No 0
SNURF-006 ENSP00000463396
ENST00000580062
Q9Y675
Show all »
Show » 71 8.4 No 0
SNURF-201 ENSP00000336543
ENST00000338094
Q9Y675
Show all »
Show » 71 8.4 No 0