ANG

GENE INFORMATION

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Gene name

ANG (HGNC Symbol)

Synonyms

RNASE5

Description

Angiogenin, ribonuclease, RNase A family, 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

21152336 - 21167130

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000214274 (version 75.37)

Entrez gene

283

UniProt

P03950 (UniProt - Evidence at protein level)

neXtProt

NX_P03950

Antibodypedia

ANG antibodies
 

PROTEIN VIEW

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ANG-001
 
ANG-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANG-001 ENSP00000336762
ENST00000336811
P03950
Show all »
Show » Show » 147 16.5 Yes 0
ANG-002 ENSP00000381077
ENST00000397990
P03950
Show all »
Show » Show » 147 16.5 Yes 0