PPP2R2A

GENE INFORMATION

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Gene name

PPP2R2A (HGNC Symbol)

Synonyms

B55A, PR52A, PR55A

Description

protein phosphatase 2, regulatory subunit B, alpha (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

Chromosome

8 (Chromosome progress)

Cytoband

p21.2

Chromosome location (bp)

26149007 - 26230196

Ensembl

ENSG00000221914 (version 73.37)

Entrez gene

5520

UniProt

P63151 (UniProt - Evidence at protein level)

neXtProt

NX_P63151

Antibodypedia

PPP2R2A antibodies
 

PROTEIN VIEW

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PPP2R2A-001
 
PPP2R2A-002
 
PPP2R2A-004
 
PPP2R2A-006
 
PPP2R2A-010
 
PPP2R2A-012
 
PPP2R2A-016
 
PPP2R2A-017
 
PPP2R2A-021
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP2R2A-001 ENSP00000370113
ENST00000380737
P63151
Show all »
Show » 447 51.7 No 0
PPP2R2A-002 ENSP00000325074
ENST00000315985
P63151
Show all »
Show » 457 53 No 0
PPP2R2A-004 ENSP00000430320
ENST00000524169
E5RFR9
Show all »
Show » 197 23 No 0
PPP2R2A-006 ENSP00000428705
ENST00000522535
3 0.4 No 0
PPP2R2A-010 ENSP00000428542
ENST00000520329
E5RHQ2
Show all »
Show » 33 3.5 No 0
PPP2R2A-012 ENSP00000428800
ENST00000523925
5 0.6 No 0
PPP2R2A-016 ENSP00000428165
ENST00000521557
14 1.6 No 0
PPP2R2A-017 ENSP00000428164
ENST00000518254
E5RJV2
Show all »
Show » 51 5.4 No 0
PPP2R2A-021 ENSP00000429279
ENST00000518397
E5RIY1
Show all »
Show » 132 14.8 No 0